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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 832140Generated: October 25, 2026

Acetic Acid → 4-[3-(4-Hydroxy-4-phenyl-piperidin-1-yl)-propyl]-1-(3-trifluoromethyl-phenyl)-[1,4]diazepan-5-one

https://huagongshe.com/reaction/832140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantPyridineHCID 1049—
ReactantBoraneHCID 6331—
Reactant4-Phenylpiperidin-4-olHCID 96387—
Reactant3-[7-Oxo-4-(3-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-propionaldehydeHCID 86638388—
Product4-[3-(4-Hydroxy-4-phenyl-piperidin-1-yl)-propyl]-1-(3-trifluoromethyl-phenyl)-[1,4]diazepan-5-oneHCID 59159246—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bf331a280a254481862148e52355929c
Source noteTest data from https://doi.org/10.1039/C8SC04228D