2,4-Bis(methylsulfonyl)-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidine → 2-Methylsulfonyl-4-(2-pyridyloxy)-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidine
Reaction equation
[CH2:30]([Li:31])[CH2:32][CH2:33][CH3:34].[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][c:7](-[c:22]2[c:23]([Cl:29])[cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[c:8](-[c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[c:9]([S:11]([CH3:12])(=[O:13])=[O:14])[n:10]1.[OH:35][c:36]1[n:37][cH:38][cH:39][cH:40][cH:41]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][c:7](-[c:22]2[c:23]([Cl:29])[cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[c:8](-[c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[c:9]([O:35][c:36]2[n:37][cH:38][cH:39][cH:40][cH:41]2)[n:10]1Participants
4
Sources & evidence
- ORD record
- ord-863d77b307024d638c88152e4ea882fa
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…