Methanesulfonyl chloride → (4-nitrophenyl)methyl N-[1-[[4-(methanesulfonamido)-2-phenylcyclopentyl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate

HRID 832228Notes

Reaction equation

[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]1[CH2:10][CH:11]([CH2:20][N:21]2[CH2:22][CH2:23][CH:24]([N:27]([CH2:28][CH:29]=[CH2:30])[C:31](=[O:32])[O:33][CH2:34][c:35]3[cH:36][cH:37][c:38]([N+:41](=[O:42])[O-:43])[cH:39][cH:40]3)[CH2:25][CH2:26]2)[CH:12]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:44][S:45](=[O:46])(=[O:47])[Cl:48]>>[NH:8]([CH:9]1[CH2:10][CH:11]([CH2:20][N:21]2[CH2:22][CH2:23][CH:24]([N:27]([CH2:28][CH:29]=[CH2:30])[C:31](=[O:32])[O:33][CH2:34][c:35]3[cH:36][cH:37][c:38]([N+:41](=[O:42])[O-:43])[cH:39][cH:40]3)[CH2:25][CH2:26]2)[CH:12]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:13]1)[S:45]([CH3:44])(=[O:46])=[O:47]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 181876031-(SR)-((t-Butoxycarbonyl)amino)-3-(SR)-((4-(N-(4-nitrobenzyloxycarbonyl)-N-(allyl)amino)piperidin-1-yl)methyl)-4-(SR)-phenylcyclopentane

Product 1

HCID 18372772(4-nitrophenyl)methyl N-[1-[[4-(methanesulfonamido)-2-phenylcyclopentyl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate

Sources & evidence

ORD record: ord-25a859327be240c1b83da3c6f30dce24
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…