Piperidine-3,4-diol → (3,4-Dihydroxypiperidin-1-yl)-[5-[4-methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl]methanone
Reaction equation
[CH3:27][NH:28][C:29]([CH:30]1[CH2:31][CH2:32][CH2:33][NH:34][CH2:35]1)=[O:36].[F:1][C:2]([c:3]1[c:4]([CH3:16])[c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13](=[O:14])[OH:15])[s:12]2)[n:6][o:7]1)([F:17])[F:18].[NH:19]1[CH2:20][CH:21]([OH:26])[CH:22]([OH:25])[CH2:23][CH2:24]1>>[F:1][C:2]([c:3]1[c:4]([CH3:16])[c:5](-[c:8]2[cH:9][cH:10][c:11]([C:13](=[O:15])[N:19]3[CH2:20][CH:21]([OH:26])[CH:22]([OH:25])[CH2:23][CH2:24]3)[s:12]2)[n:6][o:7]1)([F:17])[F:18]Participants
4
Sources & evidence
- ORD record
- ord-4253169e8ffb4a7b81b6b804bff248e7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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