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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 832387Generated: October 26, 2026

Hydrochloric Acid → 2-(tert-Butyl-dimethyl-silanyloxy)-5-{2-[4-(2-chloro-ethoxy)-phenyl]-7-methoxy-4-methyl-2H-chromen-3-yl}-pyridine

https://huagongshe.com/reaction/832387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTolueneHCID 1140—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant1-(2-Chloroethoxy)-4-iodobenzeneHCID 11358026—
Reactant3-[6-(tert-butyl-dimethyl-silanyloxy)-pyridin-3-yl]-7-methoxy-4-methyl-2H-chromen-2-olHCID 11516878—
ReactantButyllithiumHCID 178418339—
Product2-(tert-Butyl-dimethyl-silanyloxy)-5-{2-[4-(2-chloro-ethoxy)-phenyl]-7-methoxy-4-methyl-2H-chromen-3-yl}-pyridineHCID 11497511—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-111ee9e27bc64b85974becd8985be2bd
Source noteTest data from https://doi.org/10.1039/C8SC04228D