Bicarbonate Ion → 5-Chloro-7-[1,1-dimethyl-2-(2-trifluoromethyloxiranyl)ethyl]-2,3-dihydrobenzofuran
Reaction equation
[B-:30]([F:31])([F:32])([F:33])[F:34].[C:39](=[O:40])([O-:41])[O-:42].[C:45](=[O:46])([OH:47])[O-:48].[CH3:35][O+:36]([CH3:37])[CH3:38].[Cl:1][c:2]1[cH:3][c:4]([C:11]([CH2:12][C:13]([C:14]([F:15])([F:16])[F:17])([OH:18])[CH2:19][S:20][c:21]2[cH:22][cH:23][c:24]([CH3:25])[cH:26][cH:27]2)([CH3:28])[CH3:29])[c:5]2[c:6]([cH:10]1)[CH2:7][CH2:8][O:9]2.[Cl:50][CH2:51][Cl:52].[K+:43].[K+:44].[Na+:49].[OH2:53]>>[Cl:1][c:2]1[cH:3][c:4]([C:11]([CH2:12][C:13]2([C:14]([F:15])([F:16])[F:17])[O:18][CH2:19]2)([CH3:28])[CH3:29])[c:5]2[c:6]([cH:10]1)[CH2:7][CH2:8][O:9]2Participants
10
Reactant 9
HCID 769Bicarbonate Ion
HCID 813Potassium Cation2×
HCID 923Sodium ion
HCID 962Water
HCID 6344Dichloromethane
HCID 19660Carbonate Ion
HCID 26255Tetrafluoroborate
HCID 93245Trimethyloxonium
HCID 694195634-(5-Chloro-2,3-dihydro-1-benzofuran-7-yl)-1,1,1-trifluoro-4-methyl-2-[(4-methylphenyl)sulfanylmethyl]pentan-2-olProduct 1
Sources & evidence
- ORD record
- ord-8917918f7cb647099da4ee3a9ad03a60
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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