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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 832535Generated: October 25, 2026

Benzene → N-[2-{4-[3-(2-cyanoethyl)-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-1-piperidinyl}ethyl]-4-fluorobenzamide

https://huagongshe.com/reaction/832535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneHCID 241—
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantTriethylamineHCID 8471—
Reactant1-(4-Fluorobenzoyl)aziridineHCID 84853—
Reactant2,3-dihydro-2-oxo-3-(piperidin-4-yl)-1H-benzo[d]imidazol-1-propanenitrileHCID 21428924—
ProductN-[2-{4-[3-(2-cyanoethyl)-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl]-1-piperidinyl}ethyl]-4-fluorobenzamideHCID 21428991—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2c583deb8b96466e924430f669c96bcb
Source noteTest data from https://doi.org/10.1039/C8SC04228D