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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 832557Generated: October 26, 2026

Hydrochloric Acid → 6-Fluoro-5-(5-hydroxy-pent-1-ynyl)-indole-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/832557

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantPiperidineHCID 8082—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant4-Pentyn-1-olHCID 79346—
Reactant5-Bromo-6-fluoro-indole-1-carboxylic acid tert-butyl esterHCID 66884725—
ReactantHCID 178420554HCID 178420554—
Product6-Fluoro-5-(5-hydroxy-pent-1-ynyl)-indole-1-carboxylic acid tert-butyl esterHCID 69514940—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d151f40f5d41419c88d1f5af00334d5a
Source noteTest data from https://doi.org/10.1039/C8SC04228D