Boron tribromide → 4'-[(2-Chlorophenyl)sulfonyl]-3',5-difluorobiphenyl-2-ol

HRID 832685Notes

Reaction equation

HRID 832685 reaction equation
[B:27]([Br:28])([Br:29])[Br:30].[F:1][c:2]1[cH:3][c:4](-[c:18]2[c:19]([O:25][CH3:26])[cH:20][cH:21][c:22]([F:24])[cH:23]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[c:11]1[c:12]([Cl:17])[cH:13][cH:14][cH:15][cH:16]1>>[F:1][c:2]1[cH:3][c:4](-[c:18]2[c:19]([OH:25])[cH:20][cH:21][c:22]([F:24])[cH:23]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[c:11]1[c:12]([Cl:17])[cH:13][cH:14][cH:15][cH:16]1

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 672423202-Chlorophenyl 3,5'-difluoro-2'-methoxybiphenyl-4-yl sulfone

Product 1

HCID 672412524'-[(2-Chlorophenyl)sulfonyl]-3',5-difluorobiphenyl-2-ol

Sources & evidence

ORD record
ord-146c2611008e4c60aead22cbf487da19
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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