1-Methyl-4-(prop-2-yn-1-yl)piperazine → 3-Fluoro-4-(2-(3-(4-methylpiperazin-1-yl)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)aniline
Reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][C:9]#[CH:10])[CH2:6][CH2:7]1.[F:11][c:12]1[cH:13][c:14]([NH2:15])[cH:16][cH:17][c:18]1[O:19][c:20]1[c:21]2[c:22]([n:23][cH:24][cH:25]1)[cH:26][c:27]([I:29])[s:28]2>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][C:9]#[C:10][c:27]2[cH:26][c:22]3[c:21]([c:20]([O:19][c:18]4[c:12]([F:11])[cH:13][c:14]([NH2:15])[cH:16][cH:17]4)[cH:25][cH:24][n:23]3)[s:28]2)[CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-dbe2297d4acd409892deb7a75e3696b8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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