(Pyrazin-2-yl)methanamine → 2-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methyl-N-(pyrazin-2-ylmethyl)thiazole-5-carboxamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]2[s:6][cH:7][c:8]([CH2:9][N:10]3[CH2:11][CH2:12][N:13]([c:14]4[s:15][c:16]([C:17]([OH:18])=[O:19])[c:20]([CH3:21])[n:22]4)[C:23]3=[O:24])[c:25]2[cH:26]1.[F:27][c:28]1[cH:29][cH:30][c:31]([CH2:32][N:33]2[C:34](=[O:47])[N:35]([c:38]3[s:39][c:40]([C:44](=[O:45])[OH:46])[c:41]([CH3:43])[n:42]3)[CH2:36][CH2:37]2)[cH:48][cH:49]1.[n:50]1[c:51]([CH2:56][NH2:57])[cH:52][n:53][cH:54][cH:55]1>>[F:27][c:28]1[cH:29][cH:30][c:31]([CH2:32][N:33]2[C:34](=[O:47])[N:35]([c:38]3[s:39][c:40]([C:44](=[O:46])[NH:57][CH2:56][c:51]4[n:50][cH:55][cH:54][n:53][cH:52]4)[c:41]([CH3:43])[n:42]3)[CH2:36][CH2:37]2)[cH:48][cH:49]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e0630c044c5449b6ad14e25211f698b6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…