HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[3-(3-Fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester → HCID 68444797, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[3-(3-Fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 68441894 | — |
| Reactant | HCID 68442066 | HCID 68442066 | — |
| Product | HCID 68444797 | HCID 68444797 | 67% |
Reaction Steps
As described for example 90, 6-(5-methyl-3-pyridin-3-yl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (130 mg, 0.4 mmol), instead of 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester, was converted to the title compound (98 mg, 67%) which was obtained as a light yellow solid. MS: m/e=365.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846719B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-e13d860cf8c1424095b8e6ca702064d9 |
| Source note | uspto-grants-2014_09 |