[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-yl]-methanol → 2-{4-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-ylmethoxy]-naphthalen-2-yloxy}-2-methyl-propionic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]2[c:17]([OH:19])[cH:18]1)=[O:20].[CH:21]1([c:24]2[n:25][c:26](-[c:32]3[cH:33][cH:34][c:35]([C:38]([F:39])([F:40])[F:41])[cH:36][cH:37]3)[n:27][cH:28][c:29]2[CH2:30][OH:31])[CH2:22][CH2:23]1>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]2[c:17]([O:19][CH2:30][c:29]2[c:24]([CH:21]3[CH2:22][CH2:23]3)[n:25][c:26](-[c:32]3[cH:33][cH:34][c:35]([C:38]([F:39])([F:40])[F:41])[cH:36][cH:37]3)[n:27][cH:28]2)[cH:18]1)=[O:20]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-23f8415d2c774716bf207c0fe96c587b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…