HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Toluenesulfonyl chloride → 4-(4-Methyl-1-piperazinyl)-1-(4-methylbenzenesulfonyl)-1H-indole Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | 4-(4-methyl-1-piperazinyl)-1H-indole | HCID 22015351 | — |
| Product | 4-(4-Methyl-1-piperazinyl)-1-(4-methylbenzenesulfonyl)-1H-indole Hydrochloride | HCID 10135979 | — |
Reaction Steps
The title compound was prepared 4-(4-methyl-1-piperazinyl)-1H-indole and p-methylbenzenesulfonyl chloride according to Method 4 (45%): 1H NMR (CD3OD) δ 7.81–6.77 (m, 9H), 3.62–3.02 (m, 8H), 2.98 (s, 3H), 2.34 (s, 3H); MS (ESI) 370.5 (M+H)+; Purity (HPLC) >95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087750B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-681a7360d8f647d892e600b37f148d04 |
| Source note | uspto-grants-2006_08 |