Methanol → tert-butyl (1-{4-[2-(2-aminopyridin-3-yl)-5-{3-[(2-hydroxy-2-methylpropanoyl)amino]phenyl}-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}cyclobutyl)carbamate
Reaction equation
[C:1](=[O:2])([CH3:3])[O:4][C:5]([C:6](=[O:7])[NH:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[c:19]([n:20]2)[n:21](-[c:31]2[cH:32][cH:33][c:34]([C:37]4([NH:41][C:42](=[O:43])[O:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:38][CH2:39][CH2:40]4)[cH:35][cH:36]2)[c:22](-[c:24]2[c:25]([NH2:30])[n:26][cH:27][cH:28][cH:29]2)[n:23]3)[cH:12][cH:13][cH:14]1)([CH3:49])[CH3:50].[CH3:51][OH:52]>>[OH:4][C:5]([C:6](=[O:7])[NH:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][cH:17][c:18]3[c:19]([n:20]2)[n:21](-[c:31]2[cH:32][cH:33][c:34]([C:37]4([NH:41][C:42](=[O:43])[O:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:38][CH2:39][CH2:40]4)[cH:35][cH:36]2)[c:22](-[c:24]2[c:25]([NH2:30])[n:26][cH:27][cH:28][cH:29]2)[n:23]3)[cH:12][cH:13][cH:14]1)([CH3:49])[CH3:50]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-72ecb9d2a4ce43cda445cd037738b1ef
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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