1-(tert-Butoxycarbonyl)-4-methylenepyrrolidine-2-carboxylic acid → (1-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-4-methylene-pyrrolidine-1-carbonyl]-2-methyl-propyl)-carbamic acid methyl ester
Reaction equation
[C:29]([O:30][C:31]([N:32]1[CH2:33][C:34](=[CH2:35])[CH2:36][CH:37]1[C:38]([OH:39])=[O:40])=[O:41])([CH3:42])([CH3:43])[CH3:44].[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([Br:27])[cH:25][cH:26]3)[cH:19][n:20]2)[CH2:13][CH2:14][CH2:15]1)=[O:28]>>[CH3:1][O:2][C:3]([NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[C:9](=[O:10])[N:11]1[CH:12]([c:16]2[nH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([Br:27])[cH:25][cH:26]3)[cH:19][n:20]2)[CH2:13][C:14](=[CH2:29])[CH2:15]1)=[O:28]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a31ad2185988439da151976f386eb3b9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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