Tert-butyl 3-[(3-sulfanyl-2-pyridinyl)methylsulfanyl]pyrrolidine-1-carboxylate → Benzhydryl 7-[[2-(2-amino-5-chloro-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-[[1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]sulfanylmethyl]-3-pyridinyl]sulfanyl]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Reaction equation
[C:48]([CH3:49])([CH3:50])([CH3:51])[O:52][C:53](=[O:54])[N:55]1[CH2:56][CH:57]([S:60][CH2:61][c:62]2[n:63][cH:64][cH:65][cH:66][c:67]2[SH:68])[CH2:58][CH2:59]1.[CH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][C:15](=[O:16])[C:17]1=[C:24]([O:25][S:26]([C:27]([F:28])([F:29])[F:30])(=[O:31])=[O:32])[CH2:23][CH2:22][CH:21]2[N:18]1[C:19](=[O:47])[CH:20]2[NH:33][C:34]([C:35](=[N:36][O:37][CH3:38])[c:39]1[n:40][c:41]([NH2:45])[s:42][c:43]1[Cl:44])=[O:46]>>[CH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][C:15](=[O:16])[C:17]1=[C:24]([S:68][c:67]2[c:62]([CH2:61][S:60][CH:57]3[CH2:56][N:55]([C:53]([O:52][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:54])[CH2:59][CH2:58]3)[n:63][cH:64][cH:65][cH:66]2)[CH2:23][CH2:22][CH:21]2[N:18]1[C:19](=[O:47])[CH:20]2[NH:33][C:34]([C:35](=[N:36][O:37][CH3:38])[c:39]1[n:40][c:41]([NH2:45])[s:42][c:43]1[Cl:44])=[O:46]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3279ac5603074644a4a48d6d1cda766f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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