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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833320Generated: October 30, 2026

Methanol → [(5-Chloro-benzo[b]thiophen-3-yl)-[2-(3,4-difluoro-phenyl)-vinylcarbamoyl]-methyl}-methyl-phosphinic acid

https://huagongshe.com/reaction/833320

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantWaterHCID 962—
ReactantPyridineHCID 1049—
ReactantSulfuric AcidHCID 1118—
ReactantAcetonitrileHCID 6342—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantBromotrimethylsilaneHCID 76113—
Reactant{(5-Chloro-benzo[b]thiophen-3-yl)-[2-(3,4-difluoro-phenyl)-vinylcarbamoyl]-methyl}-methyl-phosphinic acid ethyl esterHCID 68526644—
Product[(5-Chloro-benzo[b]thiophen-3-yl)-[2-(3,4-difluoro-phenyl)-vinylcarbamoyl]-methyl}-methyl-phosphinic acidHCID 66871866—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e85e7f479943409dae5d1ccb2c659c83
Source noteTest data from https://doi.org/10.1039/C8SC04228D