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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 83335Generated: October 29, 2026

3-Amino-1-propanol → HCID 57520373, compound

https://huagongshe.com/reaction/83335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-1-propanolHCID 9086—
Reactant6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acidHCID 66599213—
ProductHCID 57520373HCID 5752037384%

Reaction Steps

As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (200 mg, 0.65 mmol) was converted, using 3-amino-1-propanol instead of 2-aminoethyl isopropylether, to the title compound (200 mg, 84%) which was obtained as a colourless oil. MS: m/e=368.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846719B2
Source datasetuspto-grants-2014_09
ORD IDord-64513bad54724ca6a17bba9a94906d7f
Source noteuspto-grants-2014_09