Ammonia → Methyl 6-amino-2-chloropyrimidine-4-carboxylate

HRID 833409Notes

Reaction equation

[CH3:14][S:15]([CH3:16])=[O:17].[CH3:2][O:3][C:4](=[O:5])[c:6]1[n:7][c:8]([Cl:13])[n:9][c:10]([Cl:12])[cH:11]1.[NH3:1]>>[NH2:1][c:10]1[n:9][c:8]([Cl:13])[n:7][c:6]([C:4]([O:3][CH3:2])=[O:5])[cH:11]1

Participants

Reactant 3

HCID 222Ammonia

HCID 679Dimethyl Sulfoxide

HCID 239689Methyl 2,4-dichloropyrimidine-6-carboxylate

Product 1

HCID 53396493Methyl 6-amino-2-chloropyrimidine-4-carboxylate

Sources & evidence

ORD record: ord-1bce845f87164576be895bcd59eacc9a
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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