HRID833427

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69280641

未命名化合物

HCID69280666

未命名化合物

PRODUCTS

产物

HCID69280045

N-(3,5-Difluoro-benzyl)-N'-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-isopropyl-malonamide

C33H34F2N4O3

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-af6240adb4ad4e80bb87a4735a893005
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[F:1][c:2]1[cH:3][c:4]([CH2:9][NH:10][C:35](=[O:36])[CH:37]([CH3:38])[C:39]([NH:11][CH:12]([C:13](=[O:14])[N:15]2[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[CH2:23][CH2:24]2)[CH2:25][c:26]2[cH:27][nH:28][c:29]3[cH:30][cH:31][cH:32][cH:33][c:34]23)=[O:40])[cH:5][c:6]([F:7])[cH:8]1.[F:41][c:42]1[cH:43][c:44]([CH2:45][NH:46][C:47]([CH:48]([C:49](=[O:50])[OH:51])[CH:52]([CH3:53])[CH3:54])=[O:55])[cH:56][c:57]([F:59])[cH:58]1>>[NH:11]([CH:12]([C:13](=[O:14])[N:15]1[CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[CH2:23][CH2:24]1)[CH2:25][c:26]1[cH:27][nH:28][c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]12)[C:49]([CH:48]([C:47]([NH:46][CH2:45][c:44]1[cH:43][c:42]([F:41])[cH:58][c:57]([F:59])[cH:56]1)=[O:55])[CH:52]([CH3:53])[CH3:54])=[O:51]