3-(Chloromethyl)pyridine → tert-butyl (3RS,4RS,5SR)-4-[4-(2-benzyloxy-ethoxymethyl)-phenyl]-3-(naphthalen-2-ylmethoxy)-5-(pyridine-3-ylmethoxymethyl)-piperidine-1-carboxylate
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][O:11][CH2:12][c:13]1[cH:14][cH:15][c:16]([CH:19]2[CH:20]([CH2:44][OH:45])[CH2:21][N:22]([C:37](=[O:38])[O:39][C:40]([CH3:41])([CH3:42])[CH3:43])[CH2:23][CH:24]2[O:25][CH2:26][c:27]2[cH:28][c:29]3[cH:30][cH:31][cH:32][cH:33][c:34]3[cH:35][cH:36]2)[cH:17][cH:18]1.[Cl:46][CH2:47][c:48]1[cH:49][n:50][cH:51][cH:52][cH:53]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][O:11][CH2:12][c:13]1[cH:14][cH:15][c:16]([CH:19]2[CH:20]([CH2:44][O:45][CH2:47][c:48]3[cH:49][n:50][cH:51][cH:52][cH:53]3)[CH2:21][N:22]([C:37](=[O:38])[O:39][C:40]([CH3:41])([CH3:42])[CH3:43])[CH2:23][CH:24]2[O:25][CH2:26][c:27]2[cH:28][c:29]3[cH:30][cH:31][cH:32][cH:33][c:34]3[cH:35][cH:36]2)[cH:17][cH:18]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-438ee6c2ec284971b4982ca2eda0afa2
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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