Ammonia → Imiquimod

HRID 833494Notes

Reaction equation

[CH:19](=[O:20])[NH2:21].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]2[c:11]1[n:12][cH:13][n:14]2[CH2:15][CH:16]([CH3:17])[CH3:18].[NH3:22]>>[c:2]1([NH2:21])[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]2[c:11]1[n:12][cH:13][n:14]2[CH2:15][CH:16]([CH3:17])[CH3:18]

Participants

Reactant 3

HCID 222Ammonia

HCID 713Formamide

HCID 3839614-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline

Product 1

HCID 57469Imiquimod

Sources & evidence

ORD record: ord-5f2a4aee8ef942be91a2a2595214f1fa
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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