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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 83353Generated: October 29, 2026

Azetidine → HCID 68443888, compound

https://huagongshe.com/reaction/83353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzetidineHCID 10422—
Reactant6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acidHCID 66599213—
ProductHCID 68443888HCID 6844388828%

Reaction Steps

As described for example 8b, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using azetidine instead of methylamine, to the title compound (32 mg, 28%) which was obtained as a light yellow oil. MS: m/e=350.3 [M+H]|.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846719B2
Source datasetuspto-grants-2014_09
ORD IDord-f0bfbc7d1bf345de9c08ea94ec2d86bc
Source noteuspto-grants-2014_09