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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 83367Generated: October 25, 2026

6-(5-Methyl-3-p-tolyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester → HCID 68443215, compound

https://huagongshe.com/reaction/83367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(5-Methyl-3-p-tolyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl esterHCID 68442881—
Reactant6-(5-Methyl-3-m-tolyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl esterHCID 68445236—
ProductHCID 68443215HCID 6844321578%

Reaction Steps

As described for example 250, 6-(5-methyl-3-p-tolyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (250 mg, 0.73 mmol) was converted, instead of 6-(5-methyl-3-m-tolyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester, to the title compound (210 mg, 78%) which was obtained as a white solid. MS: m/e=366.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846719B2
Source datasetuspto-grants-2014_09
ORD IDord-c0d94a92cd0642bca03b59bb9958d2be
Source noteuspto-grants-2014_09