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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833685Generated: October 25, 2026

Acetic Acid → (9-(2-(5-(2-(tert-Butyldimethylsilyloxy)ethyl)thiophen-2-yl)ethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

https://huagongshe.com/reaction/833685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant2-(5-(2-(tert-Butyldimethylsilyloxy)ethyl)thiophen-2-yl)acetaldehydeHCID 57988896—
Reactant(2-Methyl-1,3-thiazol-4-yl)-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanoneHCID 57989231—
Product(9-(2-(5-(2-(tert-Butyldimethylsilyloxy)ethyl)thiophen-2-yl)ethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanoneHCID 57989154—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-a8ab1521467544a2a4e7e1e24603dc49
Source noteTest data from https://doi.org/10.1039/C8SC04228D