Ethanol → 4-Chloro-2-fluoro-5-(2,2-difluorocyclopropylmethoxy)aniline

HRID 833694Notes

Reaction equation

HRID 833694 reaction equation
[CH3:21][CH2:22][OH:23].[Cl:1][c:2]1[cH:3][c:4]([F:18])[c:5]([N+:15]([O-:16])=[O:17])[cH:6][c:7]1[O:8][CH2:9][CH:10]1[C:11]([F:13])([F:14])[CH2:12]1.[H:19][H:20].[Pd:24]>>[Cl:1][c:2]1[cH:3][c:4]([F:18])[c:5]([NH2:15])[cH:6][c:7]1[O:8][CH2:9][CH:10]1[C:11]([F:13])([F:14])[CH2:12]1

Participants

5

Reactant 4

HCID 702EthanolHCID 23938PalladiumHCID 141294314-Chloro-2-fluoro-5-(2,2-difluorocyclopropylmethoxy)nitrobenzeneHCID 178418361HCID 178418361, compound

Product 1

HCID 141294324-Chloro-2-fluoro-5-(2,2-difluorocyclopropylmethoxy)aniline

Sources & evidence

ORD record
ord-91be77f1f2e644b9b74971b4cff798c8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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