2-Methoxybenzenesulfonyl Chloride → methyl 3-[4-(4-cyanophenyl)phenyl]-2-[[3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-7-(2-methoxyphenyl)sulfonyl-3,6,8,9-tetrahydro-2H-[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl]amino]propanoate
Reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:10][cH:11]1)[NH:20][C:21](=[O:22])[CH:23]1[NH:24][CH2:25][c:26]2[cH:27][c:28]3[c:29]([cH:30][c:31]2[CH2:32]1)[O:33][CH2:34][CH:35]([c:37]1[cH:38][cH:39][c:40]([O:43][CH2:44][c:45]2[cH:46][c:47]([Cl:52])[c:48]([Cl:51])[cH:49][cH:50]2)[cH:41][cH:42]1)[O:36]3)=[O:53].[CH3:54][O:55][c:56]1[c:57]([S:62](=[O:63])(=[O:64])[Cl:65])[cH:58][cH:59][cH:60][cH:61]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:10][cH:11]1)[NH:20][C:21](=[O:22])[CH:23]1[N:24]([S:62]([c:57]2[c:56]([O:55][CH3:54])[cH:61][cH:60][cH:59][cH:58]2)(=[O:63])=[O:64])[CH2:25][c:26]2[cH:27][c:28]3[c:29]([cH:30][c:31]2[CH2:32]1)[O:33][CH2:34][CH:35]([c:37]1[cH:38][cH:39][c:40]([O:43][CH2:44][c:45]2[cH:46][c:47]([Cl:52])[c:48]([Cl:51])[cH:49][cH:50]2)[cH:41][cH:42]1)[O:36]3)=[O:53]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0d74ec88c55740e88b72d9e80d07ec6c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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