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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833758Generated: October 26, 2026

Tetrahydrofuran → 4-Amino-5-chloro-2-methoxybenzoic acid 1-azabicyclo[3.2.1]oct-5-ylmethyl ester

https://huagongshe.com/reaction/833758

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
Reactant{1-Azabicyclo[3.2.1]octan-5-yl}methanolHCID 19795992—
ReactantButyllithiumHCID 178418339—
Product4-Amino-5-chloro-2-methoxybenzoic acid 1-azabicyclo[3.2.1]oct-5-ylmethyl esterHCID 9905330—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-02bfe6060eeb4f318dd30a2904acbb4d
Source noteTest data from https://doi.org/10.1039/C8SC04228D