Methanol → Methyl 6-amino-5-bromonicotinate

HRID 833770Notes

Reaction equation

HRID 833770 reaction equation
[CH3:12][OH:13].[NH2:1][c:2]1[c:3]([Br:11])[cH:4][c:5]([C:8](=[O:9])[OH:10])[cH:6][n:7]1.[Na+:15].[OH-:14].[OH2:16]>>[NH2:1][c:2]1[c:3]([Br:11])[cH:4][c:5]([C:8](=[O:9])[O:10][CH3:12])[cH:6][n:7]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 227420286-Amino-5-bromo-nicotinic acid

Product 1

HCID 2764099Methyl 6-amino-5-bromonicotinate

Sources & evidence

ORD record
ord-93650ed7bc7748058c2daa531d86f41d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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