1-[4-(2-Hydroxy-ethyl)-2-methyl-piperazin-1-yl]-ethanone → 1-[2-Methyl-4-[2-[4-[1-[3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-1-yl]ethanone
Reaction equation
[C:27]([CH3:28])(=[O:29])[N:30]1[CH:31]([CH3:39])[CH2:32][N:33]([CH2:36][CH2:37][OH:38])[CH2:34][CH2:35]1.[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[N:8]=[C:9]([N:12]1[CH2:13][CH2:14][CH:15]([c:18]3[cH:19][cH:20][c:21]([OH:24])[cH:22][cH:23]3)[CH2:16][CH2:17]1)[CH2:10][CH2:11]2)([F:25])[F:26]>>[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[N:8]=[C:9]([N:12]1[CH2:13][CH2:14][CH:15]([c:18]3[cH:19][cH:20][c:21]([O:24][CH2:37][CH2:36][N:33]4[CH2:32][CH:31]([CH3:39])[N:30]([C:27]([CH3:28])=[O:29])[CH2:35][CH2:34]4)[cH:22][cH:23]3)[CH2:16][CH2:17]1)[CH2:10][CH2:11]2)([F:25])[F:26]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5a7a98fbd153499d85175499fcf661dc
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…