Water → 5-amino-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-7-methyl-4H-1-benzopyran-4-one

HRID 834094Notes

Reaction equation

[C:24]([C:25]([CH3:26])([CH3:27])[CH3:28])(=[O:29])[Cl:30].[NH2:1][c:2]1[c:3]([F:23])[c:4]([CH3:22])[c:5]([F:21])[c:6]2[c:7]1[c:8](=[O:20])[cH:9][c:10](-[c:12]1[cH:13][c:14]([F:19])[c:15]([NH2:18])[cH:16][cH:17]1)[o:11]2.[OH2:31].[cH:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[NH2:1][c:2]1[c:3]([F:23])[c:4]([CH3:22])[c:5]([F:21])[c:6]2[c:7]1[c:8](=[O:20])[cH:9][c:10](-[c:12]1[cH:13][c:14]([F:19])[c:15]([NH:18][C:24]([C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[cH:16][cH:17]1)[o:11]2