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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 834111Generated: October 30, 2026

Dimethylformamide → [4-(2-tert-Butoxycarbonylaminoethylamino)-5-(4-fluorophenylcarbamoyl)pyrimidin-2-ylsulfanyl]acetic acid ethyl ester

https://huagongshe.com/reaction/834111

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantEthyl ThioglycolateHCID 12185—
ReactantDiisopropylethylamineHCID 81531—
Reactant{2-[5-(4-Fluorophenylcarbamoyl)-2-methylsulfonyl-pyrimidin-4-ylamino]-ethyl}carbamic acid tert-butyl esterHCID 69523394—
Product[4-(2-tert-Butoxycarbonylaminoethylamino)-5-(4-fluorophenylcarbamoyl)pyrimidin-2-ylsulfanyl]acetic acid ethyl esterHCID 69522205—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4d25e897ca4d4bc2ba3724f24d34da8f
Source noteTest data from https://doi.org/10.1039/C8SC04228D