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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 834171Generated: November 1, 2026

Acetonitrile → 5-Bromo-6-{2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethoxy}-nicotinic acid methyl ester

https://huagongshe.com/reaction/834171

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTriphenylphosphineHCID 11776—
ReactantDi-tert-butyl azodicarboxylateHCID 97268—
ReactantMethyl 5-bromo-6-hydroxynicotinateHCID 2764315—
Reactant2-(4-Chloro-phenyl)-1-(1-cyclohexyl-2-cyclohexylmethoxy-ethyl)-5,6-difluoro-1H-benzoimidazoleHCID 66619202—
Product5-Bromo-6-{2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethoxy}-nicotinic acid methyl esterHCID 66619325—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d88fbd29d1a44dc6911df42b7edbef3d
Source noteTest data from https://doi.org/10.1039/C8SC04228D