Sodium ion → trans-{4-[2-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester

HRID 834247Notes

Reaction equation

HRID 834247 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21]([NH:22][CH:23]1[CH2:24][CH2:25][CH:26]([CH2:29][CH:30]=[O:31])[CH2:27][CH2:28]1)=[O:32].[C:33]([O:34][BH-:35]([O:36][C:37](=[O:38])[CH3:39])[O:40][C:41](=[O:42])[CH3:43])(=[O:44])[CH3:45].[Cl:47][CH2:48][Cl:49].[N:1]1([c:7]2[n:8][o:9][c:10]3[c:11]2[cH:12][cH:13][cH:14][cH:15]3)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[Na+:46]>>[N:1]1([c:7]2[n:8][o:9][c:10]3[c:11]2[cH:12][cH:13][cH:14][cH:15]3)[CH2:2][CH2:3][N:4]([CH2:30][CH2:29][CH:26]2[CH2:25][CH2:24][CH:23]([NH:22][C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:32])[CH2:28][CH2:27]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6344DichloromethaneHCID 2724942TriacetoxyborohydrideHCID 132324753-(Piperazin-1-yl)-1,2-benzoxazoleHCID 24720884Tert-butyl trans-4-(2-oxoethyl)cyclohexylcarbamate

Product 1

HCID 59252306trans-{4-[2-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-fbacb05a0fdc4f44bb5f5baef5383a0a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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