Pyridine → Benzyl (1-cyano-3-phenylpropyl)carbamate

HRID 834364Notes

Reaction equation

HRID 834364 reaction equation
[C:1]([NH2:2])(=[O:3])[CH:4]([CH2:5][CH2:6][c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH:13][C:14]([O:15][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)=[O:23].[C:24]([N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31])([O:32][CH2:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)=[O:40].[CH3:41][C:42]([O:43][C:44](=[O:45])[CH3:46])=[O:47].[cH:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1>>[C:1](#[N:2])[CH:4]([CH2:5][CH2:6][c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH:13][C:14]([O:15][CH2:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)=[O:23]

Participants

5

Reactant 4

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 3826287Benzyl 2,5-dioxopyrrolidine-1-carboxylateHCID 76533771Benzyl (1-carbamoyl-3-phenylpropyl)carbamate

Product 1

HCID 15946346Benzyl (1-cyano-3-phenylpropyl)carbamate

Sources & evidence

ORD record
ord-5ed5b8b3d39c46ce8d4fce7cadbb6807
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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