6-(3,4-difluorophenyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-one → 6-(3,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one
Reaction equation
[F:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([CH2:20][O:21][S:22](=[O:23])(=[O:24])[CH3:25])[c:12](=[O:19])[n:13]([CH2:15][CH:16]([CH3:17])[CH3:18])[n:14]2)[cH:5][cH:6][c:7]1[CH3:8].[F:26][c:27]1[cH:28][c:29](-[c:30]2[cH:31][c:32]([CH2:33][OH:34])[c:35](=[O:36])[n:37]([CH2:38][CH:39]([CH3:40])[CH3:41])[n:42]2)[cH:43][cH:44][c:45]1[F:46]>>[F:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([CH2:20][O:21][S:22](=[O:23])(=[O:24])[CH3:25])[c:12](=[O:19])[n:13]([CH2:15][CH:16]([CH3:17])[CH3:18])[n:14]2)[cH:5][cH:6][c:7]1[F:26]Participants
3
Sources & evidence
- ORD record
- ord-9078e0800a944a7ab056ef6136caa4e5
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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