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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 834489Generated: October 25, 2026

Acetate → 4-Chloro-6-[5-chloro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-pyrimidin-2-ylamine

https://huagongshe.com/reaction/834489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
Reactant2-Amino-4,6-dichloropyrimidineHCID 65522—
Reactant2-Methylpropane-1,2-diolHCID 68410—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
Reactant5-Chloro-2-(2,2,2-trifluoro-ethoxy)-phenylboronic acidHCID 68985280—
Product4-Chloro-6-[5-chloro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-pyrimidin-2-ylamineHCID 86004362—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-10a801eea4ca4f71b2d0500d120cfdcd
Source noteTest data from https://doi.org/10.1039/C8SC04228D