HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanamine, 2,2,2-trifluoro- → HCID 68444403, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanamine, 2,2,2-trifluoro- | HCID 9773 | — |
| Edukt | 6-(3-Pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 68445257 | — |
| Produkt | HCID 68444403 | HCID 68444403 | 65% |
Reaktionsschritte
As described for example 358 g, 6-(3-pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.34 mmol) was converted using 2,2,2-trifluoroethylamine instead of 4-aminotetrahydropyran to the title compound (83 mg, 65%) which was obtained as a white solid. MS: m/e=379.3 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846719B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-47d900ce7b4a4917875571bd1aa893e0 |
| Quellennotiz | uspto-grants-2014_09 |