Methanol → 3-(4-(4-Fluorophenyl)piperidin-1-yl)propan-1-amine
Reaction equation
[CH3:30][OH:31].[F:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH2:12][N:13]([CH2:16][CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][c:23]4[c:28]3[C:26](=[O:27])[NH:25][C:24]4=[O:29])[CH2:14][CH2:15]2)[cH:8][cH:9]1.[NH2:1][NH2:2]>>[NH2:1][CH2:18][CH2:17][CH2:16][N:13]1[CH2:12][CH2:11][CH:10]([c:7]2[cH:6][cH:5][c:4]([F:3])[cH:9][cH:8]2)[CH2:15][CH2:14]1Participants
4
Sources & evidence
- ORD record
- ord-3b3cf016a98640a4a8b23875284ed50d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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