Water → HCID 178425430, compound

HRID 83496Notes

Reaction equation

HRID 83496 reaction equation
[NH2:1][C:2]1[CH:6]=[CH:5][NH:4][N:3]=1.[CH3:7][C:8](=O)[CH2:9][CH2:10][C:11](=O)[CH3:12].O>C(O)(=O)C>[CH3:12][C:11]1[N:1]([C:2]2[CH:6]=[CH:5][NH:4][N:3]=2)[C:8]([CH3:7])=[CH:9][CH:10]=1

Participants

5

Reactant 3

HCID 962WaterHCID 80352,5-HexanedioneHCID 178418806HCID 178418806, compound

Product 1

HCID 178425430HCID 178425430, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a solution of 3-aminopyrazole (100 g) in acetic acid (1000 ml) was added 2,5-hexanedione (148 ml), and the mixture was stirred for 2.4 hours at reflux. This reaction solution was cooled to room temperature, water (1000 ml) was added thereto, and the precipitated solid was collected by filtration. The resulting solid was washed with water (1000 ml), and dried under reduced pressure to give the titled compound (183 g).

Workup

  1. temperatureat reflux
  2. filtrationthe precipitated solid was collected by filtration
  3. washThe resulting solid was washed with water (1000 ml)
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-48fafc67159a496eb48bfac60f827e0e
Source dataset
uspto-grants-2014_09
Patent number
US08846746B2

Reaction notes

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