4-Chloro-3-(trifluoromethyl)aniline → 4-Pyrimidinamine, 2-chloro-N-[4-chloro-3-(trifluoromethyl)phenyl]-5-fluoro-

HRID 835047Notes

Reaction equation

HRID 835047 reaction equation
[Cl:10][c:11]1[c:12]([C:18]([F:19])([F:20])[F:21])[cH:13][c:14]([NH2:15])[cH:16][cH:17]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:15][c:14]2[cH:13][c:12]([C:18]([F:19])([F:20])[F:21])[c:11]([Cl:10])[cH:17][cH:16]2)[n:7]1

Participants

3

Reactant 2

HCID 675744-Chloro-3-(trifluoromethyl)anilineHCID 2507052,4-Dichloro-5-fluoropyrimidine

Product 1

HCID 220609674-Pyrimidinamine, 2-chloro-N-[4-chloro-3-(trifluoromethyl)phenyl]-5-fluoro-

Sources & evidence

ORD record
ord-7fd69b9944fa42bd9178863741d94662
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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