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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 835050Generated: October 27, 2026

1,1-Dichloroethane → N-Desmethyl sorafenib

https://huagongshe.com/reaction/835050

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-DichloroethaneHCID 6365—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant4-Chloro-3-(trifluoromethyl)anilineHCID 67574—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant4-(4-Aminophenoxy)pyridine-2-carboxamideHCID 23088338—
ProductN-Desmethyl sorafenibHCID 10151557—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f8162b771da445669b4148eb474f0c87
Source noteTest data from https://doi.org/10.1039/C8SC04228D