2,6-Difluorobenzenesulfonyl chloride → N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-oxazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide

HRID 835067Notes

Reaction equation

HRID 835067 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[c:18]([F:24])[c:19]([NH2:20])[cH:21][cH:22][cH:23]3)[n:10][c:11]([C:13]([CH3:14])([CH3:15])[CH3:16])[o:12]2)[n:7]1.[F:25][c:26]1[c:27]([S:33](=[O:34])(=[O:35])[Cl:36])[c:28]([F:32])[cH:29][cH:30][cH:31]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[c:18]([F:24])[c:19]([NH:20][S:33]([c:27]4[c:26]([F:25])[cH:31][cH:30][cH:29][c:28]4[F:32])(=[O:34])=[O:35])[cH:21][cH:22][cH:23]3)[n:10][c:11]([C:13]([CH3:14])([CH3:15])[CH3:16])[o:12]2)[n:7]1

Participants

3

Reactant 2

HCID 27342712,6-Difluorobenzenesulfonyl chlorideHCID 579899403-[5-(2-Chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-oxazol-4-yl]-2-fluoroaniline

Product 1

HCID 57989681N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-oxazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide

Sources & evidence

ORD record
ord-ac67877ca7fd4a91a69a07f4634cf148
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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