Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 835156Generated: October 27, 2026

Acetic Acid → (9-(2,3-Difluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(5-methylthiophen-2-yl)methanone

https://huagongshe.com/reaction/835156

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantCyano-borohydrideHCID 498716—
Reactant2,3-Difluoro-5-(2-hydroxyethyl)benzaldehydeHCID 57989102—
Reactant(5-Methylthiophen-2-yl)-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanoneHCID 57989275—
Product(9-(2,3-Difluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(5-methylthiophen-2-yl)methanoneHCID 57988906—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fd308dcf4fb14ffaa9ee45a9f03d0ef9
Source noteTest data from https://doi.org/10.1039/C8SC04228D