Potassium Cation → tert-butyl N-[1-cyano-2-[4-(3-cyanophenyl)phenyl]ethyl]carbamate

HRID 835245Notes

Reaction equation

HRID 835245 reaction equation
[C:12](#[N:13])[CH:14]([CH2:15][c:16]1[cH:17][cH:18][c:19]([I:22])[cH:20][cH:21]1)[NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30].[C:1](#[N:2])[c:3]1[cH:4][c:5]([B:9]([OH:10])[OH:11])[cH:6][cH:7][cH:8]1.[C:31](=[O:32])([O-:33])[O-:34].[K+:35].[K+:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[OH2:43]>>[C:1](#[N:2])[c:3]1[cH:4][c:5](-[c:19]2[cH:18][cH:17][c:16]([CH2:15][CH:14]([C:12]#[N:13])[NH:23][C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[cH:21][cH:20]2)[cH:6][cH:7][cH:8]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27343253-Cyanophenylboronic acidHCID 67269008(S)-tert-butyl 1-cyano-2-(4-iodophenyl)ethylcarbamate

Product 1

HCID 67269091tert-butyl N-[1-cyano-2-[4-(3-cyanophenyl)phenyl]ethyl]carbamate

Sources & evidence

ORD record
ord-911a22af6c174fb8beeb21baedcb56a7
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…