2,4-Difluorobenzylamine → N-(2,4-difluorobenzyl)-2-(2,6-difluorophenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
Reaction equation
[CH2:1]([O:2][C:4](=[O:5])[c:6]1[n:7][c:8](-[c:15]2[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]2[F:21])[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[CH3:3].[F:23][c:24]1[c:25]([CH2:26][NH2:27])[cH:28][cH:29][c:30]([F:32])[cH:31]1>>[C:4](=[O:5])([c:6]1[n:7][c:8](-[c:15]2[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]2[F:21])[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[NH:27][CH2:26][c:25]1[c:24]([F:23])[cH:31][c:30]([F:32])[cH:29][cH:28]1Participants
3
Sources & evidence
- ORD record
- ord-e97e27f47f0f41909fd8f5ac1382231b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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