5-Bromo-2-chloropyrimidine → 5-Bromo-2-[(1-cyclopentylpiperidin-4-yl)oxy]pyrimidine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][n:7]1.[OH:9][CH:10]1[CH2:11][CH2:12][N:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[CH2:14][CH2:15]1>>[c:2]1([O:9][CH:10]2[CH2:11][CH2:12][N:13]([CH:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:14][CH2:15]2)[n:3][cH:4][c:5]([Br:8])[cH:6][n:7]1Participants
3
Sources & evidence
- ORD record
- ord-75361ae839b741f4afd0e2f72eda7a47
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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