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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 835303Generated: October 27, 2026

Hydrochloric Acid → 5-Phenyl-isoxazole-3-carboxylic acid {2-oxo-2-[4-(2-trifluoromethyl-phenylamino)-piperidin-1-yl]-ethyl}-amide

https://huagongshe.com/reaction/835303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-[(5-Phenyl-1,2-oxazol-3-yl)formamido]acetic acidHCID 43354339—
ReactantPiperidin-4-yl-(2-trifluoromethylphenyl)amineHCID 54902682—
Product5-Phenyl-isoxazole-3-carboxylic acid {2-oxo-2-[4-(2-trifluoromethyl-phenylamino)-piperidin-1-yl]-ethyl}-amideHCID 57874509—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8ade112a5bfe4792bdb8af62494881c0
Source noteTest data from https://doi.org/10.1039/C8SC04228D