Dichloromethane → 4-(4-Isothiocyanato-4-methylpiperidin-1-yl)-6-methylpyrimidine

HRID 835553Notes

Reaction equation

HRID 835553 reaction equation
[C:16](=[S:17])([n:18]1[cH:19][cH:20][cH:21][cH:22][c:23]1=[O:24])[n:25]1[cH:26][cH:27][cH:28][cH:29][c:30]1=[O:31].[CH3:1][C:2]1([NH2:15])[CH2:3][CH2:4][N:5]([c:8]2[n:9][cH:10][n:11][c:12]([CH3:14])[cH:13]2)[CH2:6][CH2:7]1.[Cl:32][CH2:33][Cl:34]>>[CH3:1][C:2]1([N:15]=[C:16]=[S:17])[CH2:3][CH2:4][N:5]([c:8]2[n:9][cH:10][n:11][c:12]([CH3:14])[cH:13]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 583980494-Methyl-1-(6-methylpyrimidin-4-yl)piperidin-4-amine

Product 1

HCID 583978594-(4-Isothiocyanato-4-methylpiperidin-1-yl)-6-methylpyrimidine

Sources & evidence

ORD record
ord-179a67a80d2548e780b01f0f3b5c8ecb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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